Androgenetic alopecia (male pattern baldness and female) is by far the most common cause of hair loss in men and a serious problem for many women. There are three important components for both male and female pattern baldness:
A... A genetic predisposition for balding to occur.
B... Excessive presence of male hormones.
C... Aging - enough time for the first two factors to occur.
Both men and women produce male hormones, which play a useful role in both sexes, but the fact that androgens occur in much higher concentrations in men explains why male pattern baldness is the most common female hair loss.
DHT causes hair loss
It 's the metabolism of male hormones (androgen / testosterone), the main cause of hair loss and male and female pattern hair loss in men and women.
The metabolism of androgens includes an enzyme called 5-alpha reductase which combines with the hormone (testosterone) and converts it to DHT (dihydro-testosterone). DHT is a natural metabolite of our body.
The cause of male pattern baldness and female
Some people, both men and women are genetically predisposed to produce more DHT than the normal individuals. It is this accumulation of DHT and its effect on the cells within the hair follicle and root, which is the main cause of male and female hair loss.
When called DHT in the hair follicle and root, especially a region gets dermal papilla, it changes the cell activity and prevents necessary proteins, vitamins and minerals from providing nourishment needed to sustain life in the hair of these follicles. Consequently, the hair follicles are reproduced at a rate much slower. This reduces the growth phase (anagen phase) and lengthens or their resting phase (telogen) of the follicle. DHT causes hair follicles to shrink and even smaller and finer. This process is known as miniaturization and causes the loss of hair in order. DHT induced androgenetic aloepcia is responsible for 95% of cases of hair loss.
Blocking the synthesis of DHT at molecular level forms the basis for the treatment of androgenetic alopecia (hair loss) and FPHL (female hair loss). There are many natural DHT blockers and a number of drugs which are used for hair restoration physician.
